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Updated: Apr 23, 2026

Coherence between Brain Cortical Function and Neurocognitive Performance during Changed Gravity Conditions
Published on: May 23, 2011
Effects of carbon dioxide on physical and cognitive performance in a simulated spacesuit contingency scenario
Abstract:
Crewmembers on future Lunar and Mars surface missions will perform numerous surface exploration extravehicular activities (EVAs). NASA standards dictate a nominal upper limit to the inspired partial pressure of CO2 (PICO2) of 15 mmHg in spacesuits; however, there is no suited PICO2 standard for emergency or contingency EVA scenarios. A laboratory-based study was conducted to characterize physical and cognitive performance, and self-reported symptomology during a simulated emergency one-hour EVA return to habitat scenario while being exposed to different PICO2 levels. Fifteen healthy subjects (12 M/3 F) underwent 7 testing conditions (PICO2 of 0, 5, 10, 15, 20, 25, and 30 mmHg) using a single-blinded, repeated-measures, counterbalanced design. All subjects completed the simulated contingency EVA scenario at all PICO2 levels. Although statistically detectable dose-responses were observed in several variables, these changes did not reach levels associated with clinically or operationally relevant impairment during the one-hour exposures up to 30 mmHg PICO2.
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