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Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
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Increased vulnerability of colorectal cancer models with high alkylation damage to NTHL1 inactivation

Hyeoncheol Kim1,2, Jules Cazaubiel1,2, Tung-Lin Chiang1,3

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

Scientific Reports
|April 21, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Base excision repair (BER)Colorectal cancerDNA alkylationDNA damageSynthetic lethality

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