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Updated: Apr 23, 2026

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Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
Published on: November 10, 2023
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Reply: Optimal follow-up duration for nonspecific pleuritis: how long is long enough?
Anand Sundaralingam1,2, Rahul Bhatnagar3,4,5
1Imperial College Healthcare NHS Trust, London, UK.
ERJ Open Research
|April 22, 2026
Summary
Approximately 8% of patients with nonspecific pleuritis develop pleural malignancy. A 12-month follow-up is insufficient for patients at risk of pleural mesothelioma, necessitating extended monitoring for accurate diagnosis.
Area of Science:
- Thoracic medicine
- Oncology
- Pathology
Background:
- Nonspecific pleuritis histology is diagnosed during thoracoscopy.
- A subset of patients with this histology may develop pleural malignancy.
- Current follow-up protocols may not adequately detect delayed-onset malignancies.
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