Real-time motion correction and multicoil shim array B0 update for whole-brain MR spectroscopic imaging

Area of Science:

• Medical Imaging
• Neuroimaging
• Spectroscopy

Background:

• High-quality MRSI data is crucial for accurate metabolite quantification.
• B0 shimming and scan stability are critical factors affecting MRSI data quality.
• Integrated RF-receive/B0-shim arrays can enhance spectral quality.

Purpose of the Study:

• To develop real-time motion correction and multicoil shimming for robust whole-brain MRSI.
• To improve metabolite quantification accuracy and reproducibility in MRSI.
• To enable reliable quantitative metabolic imaging for clinical applications.

Main Methods:

• Developed a rapid navigator for head tracking and B0 fieldmapping.
• Implemented rapid processing for real-time updates of multicoil shim currents.
• Integrated RF-receive/B0-shim arrays for enhanced MRSI acquisition.

Main Results:

• Real-time motion correction and multicoil shimming led to narrower linewidths.
• Achieved higher signal-to-noise ratios and reduced quantification errors.
• Demonstrated reproducible quantitative metabolic imaging with improved spectral quality.

Conclusions:

• Whole-brain MRSI offers non-invasive brain neurochemistry mapping.
• Real-time motion correction and multicoil shimming enhance robustness and reproducibility.
• This approach supports the clinical use of quantitative metabolic imaging.