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Generalized Papulosquamous Skin Eruption in a Teenager After COVID-19 Booster
Alice J Lin1, Luis J Borda2, Katherine C Marks3
1Department of Medicine University of Pittsburgh Medical Center Pittsburgh Pennsylvania USA.
Clinical Case Reports
|April 22, 2026
Summary
Pityriasis rubra pilaris (PRP) can occur after COVID-19 vaccination. Maintain a high suspicion for PRP in patients experiencing new skin symptoms following vaccination.
Area of Science:
- Dermatology
- Immunology
- Vaccinology
Background:
- Pityriasis rubra pilaris (PRP) is a rare chronic skin disorder.
- Recent reports suggest a potential association between COVID-19 vaccination and PRP onset.
- Understanding this association is crucial for patient management.
Purpose of the Study:
- To highlight the emerging reports of pityriasis rubra pilaris (PRP) post-COVID-19 vaccination.
- To emphasize the importance of clinical vigilance for PRP in vaccinated individuals.
Main Methods:
- This is a report based on emerging clinical observations and literature review.
- No specific experimental methods were employed.
Main Results:
- Cases of pityriasis rubra pilaris (PRP) have been observed to develop after COVID-19 vaccination.
- The temporal relationship suggests a possible link requiring further investigation.
Conclusions:
- A high index of suspicion for pityriasis rubra pilaris (PRP) is warranted in patients presenting with new cutaneous symptoms after COVID-19 vaccination.
- Early recognition and diagnosis are key for appropriate patient care.
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