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Related Experiment Video

Updated: Apr 23, 2026

Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
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APEX: A Web-Based Tool for Assessing Long-Term Outdoor PM2.5 Exposure-Brief Report.

Clinton H Durney1, Aadetri Tawara1, Michael Brauer2

  • 1Department of Population Health Sciences, British Columbia Cancer Research Institute, Vancouver, Canada.

JTO Clinical and Research Reports
|April 22, 2026
PubMed
Summary
This summary is machine-generated.

The Air Pollution EXposure (APEX) tool now provides individualized annual fine particulate matter (PM2.5) exposure estimates using residential history. This advances research on air pollution

Keywords:
Air pollutionEnvironmental epidemiologyLung cancer riskPM2.5 exposure

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Area of Science:

  • Environmental Health
  • Epidemiology
  • Geographic Information Systems (GIS)

Background:

  • Long-term exposure to fine particulate matter (PM2.5) is a significant risk factor for lung cancer and other chronic diseases.
  • Accurate individualized exposure assessment is challenging due to difficulties integrating residential history with air pollution data.
  • Current methods often rely on single-address exposure estimates, limiting accuracy.

Purpose of the Study:

  • To introduce and demonstrate the Air Pollution EXposure (APEX) tool for calculating individualized annual PM2.5 exposure.
  • To provide a user-friendly, web-based application for integrating detailed residential histories with air pollution data.
  • To facilitate scalable and reproducible exposure assessment for clinical and research applications.

Main Methods:

  • Development of a web-based application (APEX) for collecting worldwide residential histories.
  • Geocoding of addresses and linkage to annual surface-level PM2.5 estimates from 1998-2024.
  • Implementation of single-entry and batch-processing modes for diverse workflow integration.

Main Results:

  • APEX provides annual PM2.5 exposure estimates based on comprehensive residential histories.
  • The tool outputs geocoded address logs and graphical summaries for user interpretation.
  • APEX-derived estimates have been successfully applied in epidemiologic studies, including lung cancer risk analysis.

Conclusions:

  • APEX offers a scalable, reproducible, and clinically applicable solution for PM2.5 exposure assessment.
  • The tool enhances personalized risk evaluation for diseases linked to air pollution.
  • APEX supports advanced epidemiologic research by enabling more accurate exposure assignment.