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Multimodal Perioperative Pain Management for Children with Medical Complexity

Kilby Mann1, David Casavant2, Dimitrios A Savva3

  • 1Department of Physical Medicine and Rehabilitation, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA.

Pediatric Clinics of North America
|April 22, 2026
PubMed

Insights

Children with medical complexity (CMC) need better pain management. A multidisciplinary approach involving caregivers and tailored multimodal analgesia is key for improved perioperative pain outcomes in CMC.

Area of Science:

  • Pediatric Anesthesiology
  • Pain Management
  • Healthcare for Children with Medical Complexity

Background:

  • Children with medical complexity (CMC) often experience inadequate pain relief during the perioperative period.
  • Current pain management strategies for CMC may not adequately address their unique needs.

Purpose of the Study:

  • To highlight the necessity of a multidisciplinary pain management approach for CMC.
  • To outline key components of effective perioperative pain management for CMC.

Main Methods:

  • Engaging CMC and/or caregivers in pain assessment.
  • Preoperative pain mitigation strategies.
  • Developing individualized treatment plans based on medical history and anticipated surgical pain.
  • Utilizing multimodal analgesia, including nonpharmacologic methods and pharmacologic agents.
  • Continuous adjustment of pain treatment plans according to the child's condition.

Main Results:

  • Multidisciplinary pain management is essential for improving perioperative pain outcomes in CMC.
  • Individualized, multimodal pain management strategies are crucial.
  • Caregiver involvement enhances pain assessment and treatment efficacy.

Conclusions:

  • A comprehensive, multidisciplinary approach is vital for optimizing perioperative pain management in CMC.
  • Tailored pain management plans incorporating multimodal analgesia and continuous reassessment are recommended.
  • Further research into specific interventions for CMC pain is warranted.

Keywords:
Children with medical complexityMultimodal analgesiaPediatric postoperative pain

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