Related Experiment Video

Updated: Apr 24, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

2.8K

Perioperative Anemia and Coagulopathy Management in Pediatric Patients with Medical Complexity

Sara Awad1, Moises Auron2, Marium Malik3

  • 1Department of Pediatric Hematology and Oncology, Cleveland Clinic Children's, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Pediatric Clinics of North America
|April 22, 2026
PubMed

Insights

Perioperative anemia and coagulopathy in medically complex children impact surgical outcomes. Early detection and management of iron deficiency anemia, alongside patient blood management, are crucial for improving patient safety and reducing complications.

Area of Science:

  • Pediatric Anesthesiology
  • Hematology
  • Surgical Patient Management

Background:

  • Perioperative anemia and coagulopathy are common in pediatric patients with medical complexity.
  • These conditions significantly affect surgical morbidity and mortality.
  • Iron deficiency anemia is the most prevalent type, necessitating prompt intervention.

Purpose of the Study:

  • To review the management of perioperative anemia and coagulopathy in pediatric patients with medical complexity.
  • To highlight the importance of early detection and treatment strategies.
  • To discuss the application of Patient Blood Management principles.

Main Methods:

  • Review of current literature and guidelines on perioperative anemia and coagulopathy in pediatric patients.
  • Emphasis on diagnostic approaches and therapeutic interventions, including iron supplementation and transfusion strategies.
  • Integration of Patient Blood Management principles and antifibrinolytic agents.

Main Results:

  • Early detection and management of iron deficiency anemia through diet and supplementation are vital.
  • Restrictive transfusion thresholds and judicious use of erythropoiesis-stimulating agents minimize complications.
  • Individualized approaches are necessary for nutritional and non-nutritional anemias like sickle cell disease.

Conclusions:

  • Effective management of perioperative anemia and coagulopathy in complex pediatric patients is achievable.
  • Patient Blood Management principles and antifibrinolytics significantly reduce bleeding and transfusion requirements.
  • Optimizing hematologic status preoperatively improves surgical outcomes and patient safety.

Keywords:
AnemiaCoagulopathyMedically complexPediatricsPerioperative management

More Related Videos

Percutaneous Hepatic Perfusion PHP with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver09:02

Percutaneous Hepatic Perfusion PHP with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver

Published on: July 31, 2016

11.4K
Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model04:55

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

Published on: May 26, 2023

1.6K

Related Concept Videos

Cardiomyopathy VII: Pre and Post Operative Nursing Management01:28

Cardiomyopathy VII: Pre and Post Operative Nursing Management

Patients with hypertrophic cardiomyopathy (HCM) and left ventricular outflow tract (LVOT) obstruction who remain symptomatic despite optimal medical therapy may undergo a septal myectomy (Morrow procedure). This procedure involves excising a portion of the hypertrophied septum below the aortic valve using a heart-lung machine to improve blood flow through the LVOT. Effective preoperative and postoperative nursing management ensures successful patient outcomes, minimizes complications, and...
454
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
624
Venous Thrombosis IV: Nursing Management01:30

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
409
Peritoneal Dialysis III: Nursing Management01:25

Peritoneal Dialysis III: Nursing Management

Peritoneal dialysis, or PD, utilizes the peritoneal membrane as a filter to eliminate excess fluid and waste products. Effective nursing management is essential for ensuring patient safety, preventing complications, and promoting optimal function of the peritoneal dialysis process.Assessment and MonitoringNurses must thoroughly assess the patient before, during, and after each dialysis session. Regular monitoring includes vital signs, daily weight, fluid intake and output, and laboratory values...
1.6K
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
543
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
398