Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gene therapy induces synaptic ribbon maturation, synaptogenesis and vision recovery in an adult dog model of retinal degeneration.

Molecular therapy. Advances·2026
Same author

Reliability, repeatability, and age associations of the dogSIT (dog Smell Interaction Test) battery in untrained companion dogs (Canis lupus familiaris).

Scientific reports·2026
Same author

Development of behavioral observation audiometry tests for companion dogs.

Applied animal behaviour science·2026
Same author

Dogs with sudden acquired retinal degeneration syndrome have evidence of a hypercoagulable state and decreased clot turnover.

Journal of the American Veterinary Medical Association·2025
Same author

Histopathologic and ultrastructural features of the choriocapillaris in dogs with sudden acquired retinal degeneration syndrome and progressive retinal atrophy.

Veterinary pathology·2025
Same author

Addressing Challenges in Developing Treatments for Inherited Retinal Diseases: Recommendations From the Third Monaciano Symposium.

Translational vision science & technology·2025

Related Experiment Video

Updated: Apr 24, 2026

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
07:41

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

5.9K

Behavioral Assessment of Vision in Dogs Using a Four-Alternative, Choice-Based Testing Device.

Freya M Mowat1,2, Simon M Petersen-Jones3

  • 1University of Wisconsin-Madison School of Veterinary Medicine, Department of Surgical Sciences, Madison, WI, USA. mowat@wisc.edu.

Methods in Molecular Biology (Clifton, N.J.)
|April 22, 2026
PubMed
Summary

This study details a method to assess dog visual navigation, crucial for evaluating treatments for canine retinal disorders. This behavioral assessment is ideal for gene therapy trials, offering a real-world measure of visual function.

Keywords:
BehaviorCanineMazeTranslational modelTunnelVisual assessment

More Related Videos

A Novel Single Animal Motor Function Tracking System Using Simple, Readily Available Software
08:22

A Novel Single Animal Motor Function Tracking System Using Simple, Readily Available Software

Published on: August 31, 2018

6.1K
A Simple Behavioral Assay for Testing Visual Function in Xenopus laevis
08:34

A Simple Behavioral Assay for Testing Visual Function in Xenopus laevis

Published on: June 12, 2014

9.3K

Related Experiment Videos

Last Updated: Apr 24, 2026

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats
07:41

Behavioral Assessment of Visual Function via Optomotor Response and Cognitive Function via Y-Maze in Diabetic Rats

Published on: October 23, 2020

5.9K
A Novel Single Animal Motor Function Tracking System Using Simple, Readily Available Software
08:22

A Novel Single Animal Motor Function Tracking System Using Simple, Readily Available Software

Published on: August 31, 2018

6.1K
A Simple Behavioral Assay for Testing Visual Function in Xenopus laevis
08:34

A Simple Behavioral Assay for Testing Visual Function in Xenopus laevis

Published on: June 12, 2014

9.3K

Area of Science:

  • Veterinary ophthalmology
  • Animal models of disease
  • Behavioral neuroscience

Background:

  • Dogs serve as significant large animal models for studying human retinal disorders.
  • Assessing visual navigation is critical for understanding real-world functional outcomes in these models.

Purpose of the Study:

  • To describe a standardized method for the behavioral assessment of visual navigation ability in dogs.
  • To establish a reliable outcome measure for therapeutic interventions targeting retinal diseases in canines.

Main Methods:

  • Development of a behavioral testing protocol to evaluate visual navigation.
  • Testing conducted across a range of luminance conditions to simulate diverse environments.
  • Focus on objective measurement of navigation performance.

Main Results:

  • A reproducible method for assessing dog visual navigation was established.
  • The protocol is adaptable to various luminance levels, enhancing its applicability.
  • Demonstrated suitability for use in clinical trials.

Conclusions:

  • The described behavioral assessment method provides a valuable tool for evaluating visual function in dogs.
  • This method is well-suited as a therapeutic trial endpoint, particularly for gene therapy studies in canine retinal disorders.
  • Offers a clinically relevant measure for assessing treatment efficacy in vision restoration research.