Related Experiment Video
Updated: Apr 24, 2026

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
Published on: October 6, 2016
Effects of exercise intervention according to functional decline risk before and after the study among
Yuya Nakajima1,2, Hidenori Onishi2, Yasutaka Mizukami2
1Department of Rehabilitation Medicine, Faculty of Health Science, Fukui Health Science University, Fukui, Japan.
Introduction:
This study aimed to clarify the effects of exercise interventions on the risk of functional decline.
Methods:
This study included community-dwelling older adults who volunteered to participate in physical fitness measurement sessions and remote exercise classes. The participants were stratified into high-risk (HR) and low-risk (LR) groups based on the cutoff value (16/17 points) of the risk assessment scale for incident functional disability. Body composition and physical function were measured before the exercise intervention, and changes were re-measured 2-3 months after the exercise.
Results:
The analysis included 65 participants with complete data. Twenty-five had HR, and 40 had LR. In the HR group, significant decreases were observed in leg muscle score, phase angle of the whole body and lower limbs, gait speed, and single-leg stance. After exercise, handgrip strength and gait speed improved significantly in both the HR (p<0.001, p<0.001) and LR (p=0.002, p<0.001) groups. Fat mass and body fat percentage also increased significantly in the HR (p=0.022, p=0.017) and LR (p=0.001, p<0.001) groups.
Conclusion:
Exercise intervention improves physical function regardless of the risk of functional decline. However, certain challenges in maintaining body composition have been observed, suggesting the need for nutritional interventions. J. Med. Invest. 73 : 143-152, February, 2026.
Related Concept Videos
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Pharmacodynamics in Geriatric Patients: Effects of Age
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be...

