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Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

775
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
775
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

793
Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
793
Cardiomyopathy VI: Nursing Management01:29

Cardiomyopathy VI: Nursing Management

476
Assessment: Nursing management of patients with cardiomyopathy begins with a thorough assessment of the patient's history, including a family history of cardiomyopathy or sudden cardiac death, personal history of heart disease, hypertension, diabetes, and any alcohol consumption or drug use.During the physical examination, assess vital signs, look for signs of heart failure (such as edema, jugular venous distention, and cyanosis), auscultate for abnormal heart sounds (like murmurs and gallops),...
476
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

930
Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
930
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

809
Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
809

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Updated: Apr 24, 2026

A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo
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Selenium deficiency-induced cardiomyopathy: a case report.

Tomonari Moriizumi1, Takahiko Nishiyama1, Shun Kohsaka1

  • 1Department of Cardiology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

European Heart Journal. Case Reports
|April 23, 2026
PubMed
Summary

Selenium deficiency can cause fatal heart conditions like non-ischaemic cardiomyopathy. Prompt selenium supplementation can reverse cardiac damage, even in dialysis patients with malabsorption.

Area of Science:

  • Cardiology
  • Trace Element Metabolism
  • Nephrology

Background:

  • Selenium is vital for redox homeostasis, thyroid function, and immune regulation.
Keywords:
Case reportCrohn’s diseaseHaemodialysisMyocardial biopsyNon-ischaemic cardiomyopathySelenium

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  • Deficiency is rare but linked to malabsorption, long-term parenteral nutrition, or dialysis.
  • It's a treatable cause of potentially fatal non-ischaemic cardiomyopathy and arrhythmias.