Related Experiment Video
Updated: Apr 24, 2026
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Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
Published on: September 14, 2018
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Neffy: A latest needle-free epinephrine
Konica Chittoria1, Arun Mukesh2, Ankur Sharma3
1Department of Anesthesiology and Critical Care, AIIMS, Jodhpur, Rajasthan, India.
Saudi Journal of Anaesthesia
|April 23, 2026
Summary
Neffy, a needle-free nasal epinephrine spray, offers a promising alternative for anaphylaxis treatment. It addresses limitations of autoinjectors, potentially improving emergency allergy care.
Area of Science:
- Allergy and Immunology
- Pharmacology
- Emergency Medicine
Background:
- Anaphylaxis is a severe allergic reaction requiring immediate epinephrine.
- Epinephrine autoinjectors are standard but face challenges like needle phobia and usability issues.
- Neffy (epinephrine nasal spray) presents a novel needle-free delivery method.
Purpose of the Study:
- To review the clinical evidence for Neffy.
- To examine its pharmacological profile, indications, and safety.
- To discuss Neffy's impact on clinical practice for anaphylaxis management.
Main Methods:
- Literature review of clinical studies on Neffy.
- Analysis of pharmacological data and safety profiles.
- Discussion of clinical practice implications.
Main Results:
- Neffy provides intranasal epinephrine delivery, bypassing needles.
- The review covers efficacy, safety, and patient-reported outcomes.
- Neffy demonstrates potential to overcome autoinjector limitations.
Conclusions:
- Neffy offers a viable needle-free option for emergency anaphylaxis treatment.
- It may improve treatment adherence and accessibility.
- Further research and clinical integration are warranted.
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