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Improving Iron Status Without Iron: Clinical Insights From Recombinant Human Lactoferrin Supplementation
Cassandra Evans1,2, Ross Peterson2, Jose Antonio1
1College of Health Care Sciences, Nova Southeastern University, Davie, USA.
Cureus
|April 23, 2026
Summary
Human lactoferrin (LF) supplements may improve iron status in women with chronic iron deficiency who don't respond well to standard iron. This case series shows promising results for effera® (LF) in boosting iron levels and energy without side effects.
Area of Science:
- Nutritional Science
- Biochemistry
- Immunology
Background:
- Chronic iron deficiency affects many women, often inadequately managed by oral iron supplements due to poor tolerance or efficacy.
- Standard iron therapies can cause gastrointestinal distress and may not fully restore iron homeostasis.
- Human lactoferrin (LF) is being explored for its potential role in iron metabolism and immune function.
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