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Mpox (Monkeypox) in Pregnancy Updates
Yeshey Dorjey1, Deep Kiran Chhetri2
1Department of Obstetrics and Gynaecology Eastern Regional Referral Hospital Mongar Bhutan.
Health Science Reports
|April 23, 2026
Summary
Mpox infection during pregnancy poses significant risks, including severe maternal illness and adverse perinatal outcomes. Prompt hospitalization, isolation, and antiviral therapy are crucial for managing pregnant individuals with Mpox.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Maternal-Fetal Medicine
Background:
- Mpox is a zoonotic viral disease with significant morbidity potential, particularly in vulnerable populations like pregnant individuals.
- Pregnancy alters immune function, increasing susceptibility to severe Mpox disease progression.
Purpose of the Study:
- To synthesize current clinical presentations, adverse outcomes, and management strategies for Mpox in pregnancy.
- To provide an evidence-based resource for obstetricians and maternal-fetal medicine specialists.
Main Methods:
- Comprehensive literature search across major electronic databases.
- Review of international guidelines from organizations including WHO, RCOG, CDC, SMFM, and ACOG.
Main Results:
- Mpox in pregnancy is linked to severe maternal illness, hospitalization, and intensive care.
- Perinatal complications include miscarriage, preterm birth, intrauterine fetal demise, congenital Mpox, low birth weight, and neurodevelopmental delays.
Conclusions:
- Pregnant individuals with Mpox require prioritized hospital admission, isolation, and antiviral treatment.
- Continuous maternal and fetal monitoring and multidisciplinary care are essential for optimizing outcomes.
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