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When the First Pulse Fades: 75% Reduction in Precedence Effect in Cochlear Implanted Rats.

Alexa N Buck1, Tim Fleiner2,3, Nicole Rosskothen-Kuhl2,3,4

  • 1Department of Neuroscience, City University of Hong Kong, Hong Kong (SAR China).

Trends in Hearing
|April 23, 2026
PubMed
Summary
This summary is machine-generated.

Cochlear implant (CI) users struggle with binaural hearing, particularly interaural time difference (ITD) discrimination. This study reveals CI stimulation flattens temporal weighting functions, reducing the precedence effect (PE) and suggesting PE requires specific auditory experience to develop.

Keywords:
cochlear implanthearing experienceprecedence effectspatial hearingtemporal integration

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Area of Science:

  • Auditory Neuroscience
  • Sensory Systems
  • Neuroscience

Background:

  • Cochlear implant (CI) users often exhibit impaired binaural hearing, especially in interaural time difference (ITD) discrimination.
  • The impact of CI stimulation on the precedence effect (PE) and developmental hearing loss remains understudied.

Purpose of the Study:

  • To investigate how CI stimulation affects the precedence effect (PE) by measuring temporal weighting functions (TWFs).
  • To compare PE in normally hearing (NH) rats with neonatally deafened (ND) and adult deafened (AD) rats receiving CI stimulation.

Main Methods:

  • Behavioral experiments in rats to measure TWFs quantifying the PE.
  • Recording lateralization responses to pulse trains with varying ITDs.
  • Probit analysis to determine the perceptual weight of each pulse.

Main Results:

  • Normally hearing rats showed significant "onset dominance" in TWFs, especially at higher pulse rates.
  • CI-stimulated rats (ND and AD) exhibited significantly flatter TWFs, with a ~75% reduction in onset dominance.
  • This reduction was more pronounced at higher pulse rates.

Conclusions:

  • CI stimulation alters temporal processing related to the precedence effect.
  • The findings suggest that the precedence effect may require specific auditory experience, such as exposure to reverberation, to develop properly.
  • Abnormal hearing experience during development or later in life impacts auditory processing in CI users.