Differentiating ante-mortem from post-mortem findings on fetal and pediatric post-mortem imaging

Area of Science:

• Forensic Radiology
• Pediatric Pathology
• Medical Imaging

Background:

• Interpreting fetal and pediatric post-mortem imaging is complex.
• Distinguishing ante-mortem pathology from post-mortem changes is crucial.
• Computed tomography (CT) and magnetic resonance imaging (MRI) have limitations in post-mortem analysis.

Purpose of the Study:

• To review normal post-mortem findings in fetal and pediatric imaging.
• To discuss the challenges in interpreting post-mortem computed tomography (PMCT) and post-mortem magnetic resonance imaging (PMMRI).
• To highlight the limitations of CT and MRI in post-mortem examinations.

Main Methods:

• Review of normal post-mortem findings across various anatomical systems.
• Discussion of imaging interpretation challenges.
• Analysis of limitations specific to PMCT and PMMRI.

Main Results:

• Detailed description of normal post-mortem changes in the central nervous system, thorax, abdomen, and musculoskeletal system.
• Identification of key differentiating features between ante-mortem pathology and post-mortem changes.
• Summary of the constraints and capabilities of PMCT and PMMRI.

Conclusions:

• Accurate interpretation of fetal and pediatric post-mortem imaging relies on understanding normal post-mortem changes.
• Knowledge of these changes and imaging limitations is essential for accurate diagnosis.
• This review provides a foundation for improved post-mortem imaging interpretation.