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Updated: Apr 25, 2026

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Electromagnetic Navigation Transthoracic Nodule Localization for Minimally Invasive Thoracic Surgery
Published on: May 4, 2022
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Ethiodized Oil Localization for Thoracoscopic Lung Nodule Resection in Children
Cecilia Gigena Heitsman1, Nicole Veyl2, Angie Ostolaza2
1Pediatric Surgery Department, Cleveland Clinic, Cleveland, Ohio.
Journal of Vascular and Interventional Radiology : JVIR
|April 23, 2026
Summary
CT-guided ethiodized oil marking is a safe and effective method for locating small pulmonary nodules in children with cancer before surgery. This technique achieved a 98.1% success rate with minimal complications in pediatric patients.
Area of Science:
- Pediatric Oncology
- Thoracic Surgery
- Medical Imaging
Background:
- Pulmonary nodules in pediatric cancer patients often require surgical resection.
- Accurate localization of small nodules is crucial for successful thoracoscopic excisional biopsy.
- Minimally invasive techniques are preferred in pediatric surgical care.
Purpose of the Study:
- To evaluate the efficacy and safety of CT-guided ethiodized oil marking for thoracoscopic excisional biopsies of pulmonary nodules in children with cancer.
- To assess the success rate and complication profile of this localization technique.
Main Methods:
- Retrospective, single-center study of 30 pediatric cancer patients (36 procedures) undergoing thoracoscopic resection of pulmonary nodules.
- Preoperative localization using CT-guided ethiodized oil marking.
- Analysis of nodule characteristics, localization success, and adverse events.
Main Results:
- 52 pulmonary nodules (mean size 3.7 mm) were resected.
- Successful localization and removal of 98.1% of nodules using ethiodized oil.
- One case of localized ethiodized oil infiltration and mild pneumothorax in 9 patients; one required chest tube placement. No hemothorax or hematoma occurred.
Conclusions:
- CT-guided ethiodized oil marking is a safe and effective method for localizing small pulmonary nodules in pediatric cancer patients.
- The technique achieves high success rates for thoracoscopic resection.
- Complications are minimal, supporting its use in this population.
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