Brain MRI Dataset Featuring a Full Clinical Protocol With and Without Intentional Motion

Kathrine Skak Madsen1, Tim Ruschke2,3, Hannah Eichhorn4,5

  • 1Danish Research Centre for Magnetic Resonance, Department of Radiology and Nuclear Medicine, Copenhagen University Hospital - Amager and Hvidovre, Hvidovre, Denmark.

Scientific Data
|April 23, 2026
PubMed

Insights

This study introduces a new dataset for Magnetic Resonance Imaging (MRI) motion correction research. It enables testing of advanced techniques for improving brain scan quality by reducing motion artifacts.

Area of Science:

  • Medical Imaging
  • Neuroimaging
  • Data Science

Background:

  • Motion artifacts in Magnetic Resonance Imaging (MRI) are prevalent, potentially obscuring pathologies or leading to misdiagnosis.
  • Current retrospective and prospective motion correction methods show promise but require thorough validation across comprehensive clinical protocols.
  • Reacquiring corrupted MRI scans is costly, highlighting the need for effective motion correction strategies.

Purpose of the Study:

  • To present a novel dataset for advancing research in MRI motion correction.
  • To facilitate the development and rigorous testing of motion correction and k-space reconstruction algorithms.
  • To address the gap in exhaustive testing of motion correction efficacy within full clinical cerebral MRI protocols.

Main Methods:

  • A dataset comprising 22 participants was created, including data with and without induced motion.
  • Data were acquired across six standard MRI sequences within a clinical cerebral MRI protocol.
  • Prospective motion correction was applied, and motion was tracked using an external device, with derived motion transforms included. Data are BIDS-compliant, with raw k-space data available.

Main Results:

  • The dataset provides paired motion-free and motion-corrupted data for direct comparison.
  • It includes comprehensive motion metadata, enabling detailed analysis of motion impact and correction effectiveness.
  • The dataset is standardized and BIDS-compliant, ensuring broad usability for the research community.

Conclusions:

  • This dataset serves as a valuable resource for developing and validating novel MRI motion correction techniques.
  • It supports research aimed at improving the diagnostic accuracy and efficiency of cerebral MRI.
  • The availability of raw k-space data further enhances its utility for advanced reconstruction method development.