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Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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Tumor Immunotherapy01:27

Tumor Immunotherapy

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Combination Therapies and Personalized Medicine02:50

Combination Therapies and Personalized Medicine

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
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Cancer Vaccines01:30

Cancer Vaccines

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Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
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Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Increased Liver Stiffness Despite Biochemical Recovery in Living Donors 1-Year Post-Hepatectomy.

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Development of a Confined-Space Suitability Index (CSSI) using Least Absolute Shrinkage and Selection Operator (LASSO) regression: a pilot study for structured fitness-for-duty screening.

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Endoscopic ultrasound-guided duodenojejunostomy for recurrent malignant duodenal obstruction after surgical gastrojejunostomy.

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Relationship between perfluoroalkyl substance exposure and immunoglobulin E among Korean adults from Korean National Environmental Health Survey cycle 4 (2018-2020): a cross-sectional study.

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Development of Aquanaut Selection Procedures: Establishing Psychological Evaluation Criteria and Processes for Underwater Space Inhabitants.

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Deep learning-based physiological risk stratification in night-shift hospital workers.

Scientific reports·2026
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Macro-Aspartate Aminotransferase Elevation in a Patient with Chronic Hepatitis B.

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Fatal Clinical Course of Hepatic Portal Venous Gas Associated with Thrombosed Abdominal Aortic Aneurysm.

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Risk Factors for Adverse Circulatory and Respiratory Events in Patients Undergoing Esophageal Endoscopic Submucosal Dissection Under Dexmedetomidine-Based Sedation.

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[Achievements and Future Directions of the National Colorectal Cancer Screening Program in Korea].

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[Advanced Combination Therapy in Inflammatory Bowel Disease].

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Related Experiment Video

Updated: Apr 25, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
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[Immunotherapy and Targeted Therapy for Advanced Biliary Tract Cancer].

Inho Lee1, Seung Bae Yoon1

  • 1Department of Internal Medicine, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

The Korean Journal of Gastroenterology = Taehan Sohwagi Hakhoe Chi
|April 24, 2026
PubMed
Summary
This summary is machine-generated.

Biliary tract cancer treatments are advancing with immunotherapy and targeted therapies. Optimizing patient selection using molecular and immune markers is key to improving outcomes for this aggressive cancer.

Area of Science:

  • Oncology
  • Cancer Research
  • Immunotherapy
Keywords:
Antineoplastic agentsCholangiocarcinomaImmunotherapyMolecular targeted therapy

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