Related Experiment Video
Updated: Apr 25, 2026

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Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
Published on: August 2, 2021
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Approaching rTMS With Openness, Awareness, and Engagement in a Combined Acceptance and Commitment Therapy Framework
Steven Wickens1, Trevor Brown1
1Both authors are with Neurocare Group, Melbourne, Australia.
Innovations in Clinical Neuroscience
|April 24, 2026
Summary
Combining repetitive transcranial magnetic stimulation (rTMS) with psychotherapy may enhance brain network flexibility, supporting psychological flexibility and meaningful change. This approach offers a synergistic, transdiagnostic intervention for diverse clinical populations.
Area of Science:
- Neuroscience
- Psychology
- Psychiatry
Background:
- Noninvasive neuromodulation, particularly repetitive transcranial magnetic stimulation (rTMS), has growing empirical support.
- The integration of psychotherapy with rTMS is an emerging area of clinical research.
Purpose of the Study:
- To review the literature on combining psychotherapy with rTMS.
- To explore this integration from a psychologist's perspective within a contextual behavioral model and neural network framework.
Main Methods:
- A narrative overview of existing studies combining psychotherapy and rTMS.
- Analysis within the framework of acceptance and commitment therapy (ACT) and implicated neural networks.
Main Results:
- rTMS-induced changes in neural network flexibility and connectivity may create a conducive neural environment for psychotherapy.
- This combination shows potential for synergistic strengthening of psychological and brain network flexibility.
- Studies reviewed span diverse clinical populations and utilize ACT principles.
Conclusions:
- rTMS can be concurrently applied with psychotherapy to foster psychological flexibility (openness, awareness, engagement).
- This combined approach can serve as a transdiagnostic, process-based intervention.
- The intervention is situated within a psychosocial and biophysiological context.
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