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Related Experiment Video

Updated: Apr 25, 2026

Doppler Optical Coherence Tomography of Retinal Circulation
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Standardized Ultra-Widefield Swept-Source OCT Imaging: A Reproducible Protocol for Peripheral Retinal Assessment.

Shivesh H Shah1,2, Ying Zhu1,2, Cade Bennett1,2

  • 1Harvard Retinal Imaging Lab, Massachusetts Eye and Ear, Boston, MA, USA.

Clinical Ophthalmology (Auckland, N.Z.)
|April 24, 2026
PubMed
Summary

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This summary is machine-generated.

A new structured imaging protocol standardizes ultra-widefield optical coherence tomography (UWF-OCT) scans. This approach improves efficiency and enables reproducible comparisons for retinal research and clinical practice.

Area of Science:

  • Ophthalmology
  • Medical Imaging

Background:

  • Ultra-widefield (UWF) photography and UWF-OCT are increasingly used in retina clinics.
  • Current navigated swept-source OCT (SS-OCT) systems lack standardized protocols, hindering comparative studies.
  • This limitation impacts longitudinal patient monitoring and population-based research.

Purpose of the Study:

  • To present a structured imaging protocol for UWF-OCT.
  • To address the limitations of non-standardized imaging protocols in current clinical practice.
  • To facilitate reproducible comparisons across patient visits and in population studies.

Main Methods:

  • A universal template standardizes seven scans per patient (three 21 mm line scans, four UWF volume scans).
  • Scans are automatically positioned according to the protocol.
Keywords:
age-related macular degenerationdiabetic retinopathyperipheral retinastandardized protocolultrawidefield optical coherence tomography

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  • Images are stitched into a composite for enhanced comparison.

    • Main Results:

    • The protocol standardizes scan acquisition for navigated SS-OCT.
    • Composite images are optimized for longitudinal and inter-patient comparisons.
    • The protocol enhances efficiency and reproducibility of peripheral retinal assessments.

    Conclusions:

    • The proposed structured UWF-OCT protocol improves data consistency.
    • This standardization is crucial for reliable clinical and research applications.
    • The protocol shows potential for adaptation to other UWF systems and clinical evaluation.