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Minimal Change Disease: A Case of Delayed Recognition Due to Chronic Lower Extremity Edema
Grant Corven1, Sarah Baker1, Delmis Perez Castro1
1Internal Medicine, Naples Comprehensive Health (NCH) Healthcare System, Naples, USA.
Abstract:
We present the case of a 79-year-old woman with new-onset nephrotic syndrome discovered by working up worsening lower extremity edema. Renal biopsy showed a pathology report consistent with minimal change disease (MCD). The patient was treated with prednisone and, subsequently, tacrolimus with good clinical response and improvement in her serum albumin and total protein levels upon outpatient follow-up. This case underscores the importance of a broad differential for the common complaint of lower extremity edema and the additional risks of MCD and adverse effects of its treatment.
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