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Updated: Apr 25, 2026

Preparation of Primary Acute Lymphoblastic Leukemia Cells in Different Cell Cycle Phases by Centrifugal Elutriation
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Philadelphia Chromosome-Positive B-cell Acute Lymphoblastic Leukemia: A Case Report.

Alireza Izadian Bidgoli1, Alberto Gomez Veliz2, Shabnam Yazdanpanah1

  • 1Medical School, American University of the Caribbean School of Medicine, Cupecoy, SXM.

Cureus
|April 24, 2026
PubMed
Summary

This case study details a successful treatment approach for Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia (Ph+ B-ALL) in an elderly patient. The findings emphasize tailored, reduced-intensity therapy leading to remission.

Area of Science:

  • Hematology
  • Oncology
  • Geriatrics

Background:

  • Philadelphia chromosome-positive B-cell acute lymphoblastic leukemia (Ph+ B-ALL) is a high-risk subtype in older adults.
  • Comorbidities in elderly patients often complicate treatment decisions and limit intensive management options.
Keywords:
acute lymphoblastic leukemia (all)bcr-abl1 rearrangementdasatinibleukemiaphiladelphia chromosome-positive b-cell acute lymphoblastic leukemia (ph+ b-all)remission

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