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Updated: Apr 25, 2026

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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
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Recurrent In-Stent Restenosis Treated With a Novel Technique: The Double-DCB Technique.
An Shing Ang1, Thet Khaing1, Bharat Khialani2
1Department of Cardiology, Woodlands Hospital, Singapore.
JACC. Case Reports
|April 24, 2026
Summary
Recurrent in-stent restenosis after percutaneous coronary intervention can be treated with a novel double-drug-coated balloon (DCB) technique. This approach avoids additional metal implants, offering a promising alternative for managing complex coronary artery disease.
Area of Science:
- Interventional Cardiology
- Cardiovascular Medicine
- Medical Technology
Background:
- Percutaneous coronary intervention (PCI) is crucial for acute and chronic coronary syndrome.
- In-stent restenosis (ISR) after PCI remains a significant challenge, increasing adverse outcomes.
- Current treatments for ISR often involve repeat stenting, adding more metal layers.
