Recurrent In-Stent Restenosis Treated With a Novel Technique: The Double-DCB Technique

An Shing Ang1, Thet Khaing1, Bharat Khialani2

  • 1Department of Cardiology, Woodlands Hospital, Singapore.

JACC. Case Reports
|April 24, 2026
PubMed

Insights

Recurrent in-stent restenosis after percutaneous coronary intervention can be treated with a novel double-drug-coated balloon (DCB) technique. This approach avoids additional metal implants, offering a promising alternative for managing complex coronary artery disease.

Area of Science:

  • Interventional Cardiology
  • Cardiovascular Medicine
  • Medical Technology

Background:

  • Percutaneous coronary intervention (PCI) is crucial for acute and chronic coronary syndrome.
  • In-stent restenosis (ISR) after PCI remains a significant challenge, increasing adverse outcomes.
  • Current treatments for ISR often involve repeat stenting, adding more metal layers.