Revisiting Myositis Ossificans: A Comprehensive Stage-by-Stage Imaging Review.

Area of Science:

• Radiology
• Orthopedic Pathology
• Medical Imaging

Background:

• Myositis ossificans (MO) is a benign heterotopic ossification, often post-traumatic.
• Early imaging may resemble aggressive soft-tissue tumors, complicating diagnosis.
• This can lead to unwarranted biopsies or surgeries.

Purpose of the Study:

• To provide an updated overview of MO classification, pathophysiology, and imaging.
• To focus on the time-dependent evolution of radiologic appearances.
• To aid in distinguishing MO from other lesions and guide management.

Main Methods:

• Narrative review of existing literature.
• Analysis of radiologic findings across different imaging modalities.
• Discussion of disease staging and diagnostic clues.

Main Results:

• MO imaging findings evolve over time, showing characteristic zonal phenomena and peripheral maturation.
• Key features help differentiate MO from soft-tissue sarcomas and other ossified lesions.
• Understanding these evolving patterns is crucial for accurate diagnosis.

Conclusions:

• Accurate diagnosis of MO relies on recognizing its dynamic imaging spectrum.
• Radiologists and clinicians must understand these features to guide management and prevent overtreatment.
• Imaging plays a vital role in diagnosis and patient follow-up.