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Dose-Dependent Impacts of Fluoride Exposure on Behavior, Oxidative Stress, Liver Metabolism, and Molecular responses

Syed Sikandar Habib1, Rim El Amouri2, Fariha Latif3

  • 1Department of Zoology, University of Sargodha, Sargodha Punjab, 40100, Pakistan.

Ecotoxicology (London, England)
|April 24, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Cyprinus carpioFluoridebehavioral alterationsimmune signalingmetabolitesoxidative stress

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Drug toxicities can be stratified into pharmacological, pathological, or genotoxic based on their mechanisms. The incidence and severity of these toxicities generally increase with the drug's concentration in the body and exposure time.Pharmacological toxicity is evident when the therapeutic effects of drugs overshoot into adverse reactions in a predictable, dose-dependent manner. Central nervous system (CNS) depression from barbiturates is a classic example, with effects escalating from...
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