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Mask-Guided Proxy Mining Network for Few-Shot Medical Image Segmentation.

Wendong Huang, Jinwu Hu, Yongchao Wang

    IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society
    |April 24, 2026
    PubMed
    Summary
    This summary is machine-generated.

    Few-shot medical image segmentation (FSMIS) is improved by the novel mask-guided proxy mining network (MPMNet). MPMNet reduces ambiguity and enhances segmentation accuracy by mining representative features, outperforming existing methods.

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    Area of Science:

    • Medical Image Analysis
    • Computer Vision
    • Artificial Intelligence

    Background:

    • Few-shot medical image segmentation (FSMIS) methods rely on limited labeled data for new classes.
    • Current FSMIS approaches use pixel-level correlations, which can cause mismatches and semantic ambiguity due to class information gaps.

    Purpose of the Study:

    • To introduce a novel Mask-Guided Proxy Mining Network (MPMNet) to address foreground-background ambiguity in FSMIS.
    • To improve the accuracy and robustness of medical image segmentation with limited data.

    Main Methods:

    • MPMNet mines representative features (proxies) from support and query images to resolve ambiguity.
    • A mask-guided proxy mining module adaptively learns proxies to handle variations in scale and shape.
    • Hierarchical prior generation and context-aware feature enrichment modules enhance multi-scale information and feature discriminability.

    Main Results:

    • MPMNet effectively overcomes false pixel matches by establishing proxy-level semantic correlations.
    • Experiments on three benchmarks show MPMNet significantly outperforms state-of-the-art methods.
    • A mean gain of 2.71% in Dice Similarity Coefficient (DSC) was achieved across datasets.

    Conclusions:

    • MPMNet offers a robust solution for FSMIS by mitigating semantic ambiguity.
    • The proposed network architecture enhances segmentation performance in low-data regimes.
    • The approach demonstrates significant improvements in medical image segmentation accuracy.