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Drugs that Stabilize Microtubules

Drugs that Stabilize Microtubules

Microtubules are dynamic structures that undergo cycles of catastrophe and rescue. The microtubules play a central role in cell division by forming the spindle apparatus for segregating the chromosomes. This makes them ideal targets for regulating dividing cells in tumors and malignant cancer cells. Microtubule stabilizing drugs help stabilize the microtubule formation and promote its polymerization. Paclitaxel was the first microtubule stabilizing agent used as anticancer drug in chemotherapy...

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Related Experiment Video

Updated: Apr 26, 2026

Long-term Live-cell Imaging to Assess Cell Fate in Response to Paclitaxel

Long-term Live-cell Imaging to Assess Cell Fate in Response to Paclitaxel

Published on: May 14, 2018

Resolving paclitaxel efficacy

Jawdat Al-Bassam¹, Aryan Taheri^2,3

¹Department of Molecular Cellular Biology, University of California, Davis, Davis, CA, USA. jmalbassam@ucdavis.edu.

Nature Chemical Biology

|April 24, 2026

Summary

No abstract available in PubMed .

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