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Hyperdiluted Triamcinolone Injections for Nasal and Alar Contouring.

Kyu-Ho Yi1, Suyeon Lee2, Jong Keun Song3

  • 1You and I Clinic, Seoul, Republic of Korea.

Journal of Cosmetic Dermatology
|April 25, 2026
PubMed
Summary
This summary is machine-generated.

This study introduces a new nonsurgical method for nasal contour refinement using hyperdiluted triamcinolone acetonide (TAC) microinjections. The technique offers targeted soft-tissue reduction for subtle aesthetic improvements without surgery or added volume.

Keywords:
Intralesionalcosmetic techniquesglucocorticoidsinjectionsnosetriamcinolone Acetonide

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Area of Science:

  • Dermatology
  • Plastic Surgery
  • Aesthetic Medicine

Background:

  • Increasing demand for minimally invasive nasal contour refinement without surgery or volume augmentation.
  • Hyaluronic acid fillers offer contour alteration but add volume and carry vascular risks.
  • Intralesional corticosteroids induce soft-tissue thinning, previously used for postoperative supratip fullness.

Purpose of the Study:

  • To present a novel nonsurgical, nonfiller technique for nasal soft-tissue reduction.
  • Utilizing hyperdiluted triamcinolone acetonide (TAC) microinjections for targeted nasal and alar fullness.
  • Establishing a case-series protocol with standardized Global Aesthetic Improvement Scale (GAIS) reporting.

Main Methods:

  • Twenty adult patients received a 10-point microinjection protocol with hyperdiluted TAC (approx. 1.3 mg/mL).
  • 1.0 mL was administered per session, repeated every 3 weeks for five sessions.
  • Cumulative TAC dose per patient was approximately 6.5 mg.

Main Results:

  • Patient-reported outcomes were assessed using the Global Aesthetic Improvement Scale (GAIS) at final follow-up.
  • The study provides a patient-level GAIS reporting framework for transparent outcome documentation.
  • The technique aims for gradual, localized soft-tissue thinning via minimized corticosteroid exposure.

Conclusions:

  • Hyperdiluted TAC microinjections represent a distinct approach from surgical rhinoplasty and filler-based methods.
  • This technique offers a potential solution for patients seeking subtle nasal soft-tissue reduction.
  • The described protocol and reporting framework facilitate reproducible and transparent results in nonsurgical rhinoplasty.