Related Experiment Video
Updated: Apr 27, 2026

A Real-World High-Intensity Interval Training Protocol for Cardiorespiratory Fitness Improvement
Published on: February 22, 2022
Evaluating maximal oxygen uptake in exercise-based cardiac rehabilitation
Claus Theilgaard Sevel1, Ulrik Dalgas2, Martin Langeskov-Christensen2,3
1Research Center for activity and Prevention, Department of Physiotherapy, VIA University College, Aarhus N, Denmark.
Maximal oxygen uptake (VO2max) assessment in cardiac rehabilitation is feasible using a VO2 plateau cut-off of ≤100 mL. Secondary criteria like respiratory exchange ratio and perceived exertion can confirm maximal effort when a plateau isn't reached.
Area of Science:
- Cardiology
- Exercise Physiology
- Preventive Medicine
Background:
- Maximal oxygen uptake (VO2max) is a critical health and performance indicator, especially for individuals with heart disease, predicting mortality.
- Cardiopulmonary exercise testing is the gold standard for VO2max but is underutilized in primary healthcare.
- Cardiac rehabilitation programs can benefit from accessible VO2max assessment methods.
Purpose of the Study:
- To evaluate standard criteria for assessing VO2max in patients undergoing cardiac rehabilitation.
- To determine the suitability of VO2 plateau cut-offs in a primary healthcare setting.
- To identify reliable secondary criteria for confirming maximal effort during exercise testing.
Main Methods:
- A cross-sectional study involving 93 participants in a primary healthcare cardiac rehabilitation program.
- Cycle ergometer exercise tests were performed to determine VO2max.
- Primary validation used VO2 plateau cut-offs (≤50 and ≤100 mL O2/min); secondary criteria included respiratory exchange ratio (RER), rate of perceived exertion (RPE), and maximal heart rate.
Main Results:
- A VO2 plateau was achieved by 88% of participants using the ≤100 mL cut-off.
- 61% of participants met at least two secondary criteria, confirming maximal effort.
- The ≤100 mL cut-off demonstrated good utility in this population.
Conclusions:
- A VO2 plateau cut-off of ≤100 mL is a potentially suitable criterion for VO2max assessment in primary healthcare cardiac rehabilitation.
- When a plateau is not reached, RER ≥1.15 and RPE ≥17 can effectively indicate maximal effort.
- These findings support the integration of standardized VO2max testing in cardiac rehabilitation settings.
More Related Videos
07:26Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
12:37Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine
Published on: February 9, 2016
Related Concept Videos
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be...
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Cardiac Output and Stroke Volume
In an average resting adult male, the typical cardiac...
Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
Pathophysiology of Cardiac Performance