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Feasibility and Safety of Same-Day Discharge Following Elective Mitral Transcatheter Edge-to-Edge Repair

Mahmoud Ismayl1, Andrew M Goldsweig2, Mohamad Alkhouli3

  • 1Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, USA.

JACC. Advances
|April 25, 2026
PubMed
Abstract

Insights

Same-day discharge (SDD) after mitral transcatheter edge-to-edge repair (M-TEER) is rare but safe. This approach shows similar 90-day readmission risks and lower costs compared to next-day discharge (NDD).

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Health Services Research

Background:

  • Limited data exists on the feasibility and safety of same-day discharge (SDD) after mitral transcatheter edge-to-edge repair (M-TEER).
  • Evaluating contemporary trends and outcomes of SDD following M-TEER is crucial for clinical practice.

Purpose of the Study:

  • To assess trends in same-day discharge (SDD) versus next-day discharge (NDD) after elective mitral transcatheter edge-to-edge repair (M-TEER).
  • To compare the safety and economic outcomes of SDD versus NDD after M-TEER.

Main Methods:

  • A retrospective analysis of the Nationwide Readmissions Database (2016-2022) was conducted.
  • Elective M-TEER hospitalizations were categorized into SDD, NDD, and second- or third-day discharge (ScD/TDD).
  • Cox proportional hazards regression was used to compare 90-day unplanned all-cause readmissions, 90-day heart failure readmissions, and index hospitalization costs.

Main Results:

  • The proportion of SDD increased from 0.4% to 2.4% between 2016 and 2022, while ScD/TDD decreased significantly.
  • SDD was associated with similar 90-day all-cause readmission (14.8% vs 12.5%) and heart failure readmission (4.4% vs 3.7%) risks compared to NDD.
  • SDD resulted in significantly lower index hospitalization costs ($38,029 vs $43,319; P=0.03) compared to NDD.

Conclusions:

  • Same-day discharge (SDD) following M-TEER is infrequently utilized but demonstrates comparable safety regarding 90-day readmissions to next-day discharge (NDD).
  • SDD is associated with reduced index hospitalization costs, suggesting potential economic benefits.
  • Further research is needed to define optimal patient selection criteria for SDD after M-TEER.
Keywords:
M-TEERmitral transcatheter edge-to-edge repairoutcomesreadmissionssame-day discharge

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