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Updated: Apr 27, 2026

Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters
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Monitoring Cell-autonomous Circadian Clock Rhythms of Gene Expression Using Luciferase Bioluminescence Reporters

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Whole-transcriptome insights into light-responsive non-coding RNA networks regulating circadian clock and DNA repair

Shuang Wang1, Zhirui Zhu1, Minjian Zou1

  • 1School of Life Sciences, Lanzhou University, No. 222 South Tianshui Road, Lanzhou, Gansu Province, 730000, China.

Functional & Integrative Genomics
|April 25, 2026
PubMed
Summary

No abstract available in PubMed .

Keywords:
Circadian clockDNA repairLightNon-coding RNAsRegulatory networksZebrafish model

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The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
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