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Updated: Apr 28, 2026

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions

DTI of the Visual Pathway - White Matter Tracts and Cerebral Lesions

Published on: August 26, 2014

BundleParc: Consistent white matter bundle parcellation without tractography.

Antoine Théberge¹, Zineb El Yamani², Muhamed Barakovic³

¹Videos & Images Theory and Analytics Laboratory (VITAL), Faculté des Sciences, Université de Sherbrooke, 2500 Bd. de l'Université, Sherbrooke, J1K2R1, QC, Canada; Sherbrooke Connectivity and Imaging Lab (SCIL), Faculté des Sciences, Université de Sherbrooke, 2500 Bd. de l'Université, Sherbrooke, J1K2R1, QC, Canada.

Medical Image Analysis

|April 26, 2026

Summary

This summary is machine-generated.

BundleParc offers a new, simpler method for white matter (WM) bundle parcellation. This tractography-free approach improves accuracy and reproducibility in neuroimaging studies.

Keywords:

Deep learning Diffusion MRI Tractography Tractometry

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Area of Science:

Neuroimaging
White Matter Anatomy
Computational Neuroscience

Background:

Tractometry analyzes microstructural properties of white matter (WM) tracts.
Accurate white matter bundle parcellation is crucial for tractometry.
Current methods are inconsistent, computationally expensive, and lack reproducibility.

Purpose of the Study:

Introduce BundleParc, a novel, tractography-free bundle parcellation method.
Develop a consistent, accurate, and reproducible parcellation technique.
Simplify and enhance the utility of white matter bundle segmentation.

Main Methods:

BundleParc directly maps fiber orientation distribution function (fODF) volumes to label maps.
Avoids computationally intensive streamline generation and tractography.
Utilizes a direct mapping approach for parcellation.

Main Results:

BundleParc demonstrates superior accuracy, robustness, and reproducibility compared to state-of-the-art methods.
The method is significantly simpler and faster than existing tract-based profiling techniques.
Evaluations on research and clinical cohorts confirm its effectiveness.

Conclusions:

BundleParc provides a consistent and tractography-free solution for bundle parcellation.
It offers a significant advancement for reproducible and efficient white matter analysis.
The method is suitable for fast, easy-to-use, off-the-shelf bundle segmentation.