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Related Concept Videos

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

414
Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
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Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration01:25

Extracorporeal Removal of Drugs: Hemoperfusion and Hemofiltration

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Hemoperfusion and hemofiltration are critical techniques in medical treatments to eliminate accumulated drugs, metabolites, and electrolytes from the bloodstream. These methods are particularly vital in cases of accidental poisoning and drug overdose.Hemoperfusion involves passing blood through an adsorbent material to remove unwanted substances. The main adsorbents used in hemoperfusion include activated charcoal and Amberlite resins. Activated charcoal can adsorb both polar and nonpolar...
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Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

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Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
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Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Articles linked to this work by shared authors, journal, and citation graph.

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Effects of sodium glucose transporters 2-inhibitors on body mass index and systolic blood pressure in kidney transplant recipients with or without diabetes mellitus: a multicenter propensity score-matched analysis.

American journal of nephrology·2026
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Related Experiment Video

Updated: Apr 28, 2026

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting
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Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting

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[Application of a Sequential Blood Purification Approach in a Complex Critically Ill Patient].

Valentina Zanetti1, Sara Cavagnaro2, Novella Evelina Conti3

  • 1SCDU Nefrologia e Dialisi, AOU SS Antonio e Biagio e Cesare Arrigo, Alessandria.

Giornale Italiano Di Nefrologia : Organo Ufficiale Della Societa Italiana Di Nefrologia
|April 27, 2026
PubMed
Summary

This case report details managing major trauma with multiorgan failure using advanced extracorporeal blood purification. Sequential use of high cut-off filters, hemoadsorption, and multifunctional membranes led to full renal and hepatic recovery.

Area of Science:

  • Intensive Care Medicine
  • Nephrology
  • Toxicology

Background:

  • Major trauma presents significant intensive care challenges, frequently leading to multiorgan failure.
Keywords:
acute kidney injurycontinuous kidney replacement therapycrush syndromehemoadsorptionsepsis

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  • Pelvic crush injuries can precipitate severe complications like rhabdomyolysis, acute kidney injury, septic shock, and liver dysfunction.