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Updated: Apr 28, 2026

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Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
Published on: February 17, 2018
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Clozapine-Associated Myocarditis Presenting With Acute Heart Failure: Inflammation Before Injury
Pahresah Roomiany1, Anisa Eshraghi2, Faye Farber1
1Hospital Medicine, Duke University Health System, Durham, USA.
Cureus
|April 27, 2026
Summary
Clozapine can cause myocarditis, a serious heart condition. Early detection using inflammatory markers like C-reactive protein can lead to prompt treatment and full recovery in patients with treatment-resistant schizophrenia.
Area of Science:
- Cardiology
- Psychiatry
- Pharmacology
Background:
- Clozapine is a vital antipsychotic for treatment-resistant schizophrenia.
- Clozapine-induced myocarditis is a rare but severe adverse effect.
- Early symptoms of myocarditis are often non-specific, delaying diagnosis.
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