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Correlation between serum triglycerides and prostate cancer risk in Chinese men: a meta-analysis
Yuan Liu1, Fei Wei1, Yongxiang Yi1
1Department of Urology, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Background:
Epidemiological research presents inconsistent findings on the association between serum triglyceride levels and the risk of developing prostate cancer. However, a systematic review and meta-analysis study on the relationship between triglyceride levels and the risk of prostate cancer in Chinese men are limited.
Methods:
We explored PubMed, Wanfang, and the China National Knowledge Infrastructure (CNKI) databases to find related retrospective studies on the link between serum triglycerides and prostate cancer. The Newcastle-Ottawa Scale was employed to assess the quality of the study. To compute the pooled odds ratios (OR), a random effects model was utilized.
Results:
Twelve studies were included, comprising 4732 cases. For prostate cancer, the OR for serum triglyceride levels were 1.03 (95%CI:0.755-1.404, P=0.898). Furthermore, subgroup analysis indicated no link between serum triglyceride levels and prostate cancer risk.
Conclusion:
We observed no relationship between serum triglyceride and the likelihood of prostate cancer in Chinese men. Due to wide confidence intervals, these results require cautious interpretation and confirmatory replication.
