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Personalized Vestibular Rehabilitation in Persistent Postural-Perceptual Dizziness (PPPD), Unilateral and Bilateral
Pasqualina Maria Picciotti1, Rolando Rolesi2, Giorgia Rossi2
1Dipartimento di Testa-Collo e Organi di Senso, Catholic University of the Sacred Heart, 00168 Rome, Italy.
Journal of Personalized Medicine
|April 27, 2026
Summary
Vestibular rehabilitation effectively treats vestibular disorders but shows limited impact on Persistent Postural-Perceptual Dizziness (PPPD) posturography. While VR improves quality of life for PPPD patients, further research is needed for definitive conclusions.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Audiology
Background:
- Vestibular rehabilitation (VR) is established for unilateral and bilateral vestibular disorders.
- Its efficacy in Persistent Postural-Perceptual Dizziness (PPPD) remains debated.
- This study investigates VR with computerized dynamic posturography (CDP) as a standalone therapy for PPPD.
Purpose of the Study:
- To evaluate the efficacy of VR using CDP in PPPD patients.
- To compare VR outcomes in PPPD with those in unilateral vestibular vestibulopathy (UVP) and bilateral vestibular vestibulopathy (BVP).
- To define VR's role in personalized therapy for different vestibular disorders.
Main Methods:
- 44 patients with UVP (n=19), BVP (n=10), and PPPD (n=15) were assessed.
- Methods included bedside vestibular assessment, VNG, vHIT, CDP, and Dizziness Handicap Inventory (DHI).
- Patients received 5 weekly VR sessions and daily home exercises.
Main Results:
- VR significantly improved quality of life and reduced handicap in UVP and BVP patients (improved DHI and CDP).
- In PPPD patients, VR did not significantly alter CDP results.
- PPPD patients showed improved DHI functional sub-score but not overall DHI score.
Conclusions:
- VR is effective for unilateral and bilateral peripheral vestibulopathies.
- VR with CDP may offer subjective benefits for PPPD patients, improving handicap and daily functioning.
- Limitations include a small sample size and lack of a control group, precluding definitive conclusions for PPPD efficacy.
Keywords:
Computed Dynamic PosturographyDizziness Handicap InventoryPPPDbilateral vestibular lossdizzinessunilateral vestibular lossvestibular rehabilitationMore Related Videos
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