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Related Concept Videos

Cranial Bones: Lateral View01:27

Cranial Bones: Lateral View

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The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
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Sphenoid sinus osteitis after endoscopic transsphenoidal surgery: a bone-centered postoperative entity.

Burak Çabuk1, Atılay Yaylacı2, Fatih Shatri3

  • 1Department of Neurosurgery, Kocaeli University, Kocaeli, Türkiye, 41001. burak.cabuk@kocaeli.edu.tr.

Acta Neurochirurgica
|April 27, 2026
PubMed
Summary
This summary is machine-generated.

Sphenoid sinus osteitis is a rare complication after endoscopic transsphenoidal surgery (ETS), primarily linked to sellar reconstruction. Early recognition and surgical revision lead to favorable outcomes for patients experiencing symptoms like cacosmia.

Keywords:
EndoscopicOsteitisPituitarySfenoid sinusSinusitisSkull base

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Area of Science:

  • Otolaryngology
  • Neurosurgery
  • Skull Base Surgery

Background:

  • Postoperative sinonasal inflammation after endoscopic skull base surgery is not well understood.
  • Sphenoid sinus osteitis is an underrecognized complication following endoscopic transsphenoidal surgery (ETS).
  • Conventional assessments focus on mucosal pathology, overlooking bone-centered issues.

Purpose of the Study:

  • To determine the incidence of sphenoid sinus osteitis after ETS.
  • To describe the clinical and radiological features of this condition.
  • To identify surgical and demographic risk factors associated with its development.

Main Methods:

  • Retrospective review of 1,443 patients undergoing primary ETS for sellar/parasellar tumors (Sept 2021-Sept 2024).
  • High-resolution CT scans assessed osteitis using the Lee and Kennedy classification.
  • Clinical symptoms (cacosmia) and surgical techniques (reconstruction) were analyzed for risk factors.

Main Results:

  • Sphenoid sinus osteitis occurred in 12 cases (0.83%), exclusively in patients with sellar reconstruction (p < 0.001).
  • Cacosmia was the primary symptom in 75% of affected patients (p < 0.001).
  • Surgical revision was needed for 91.7% of patients, with complete symptom resolution at 12 months.

Conclusions:

  • Sphenoid sinus osteitis is a rare but significant bone-centered complication of ETS, distinct from mucosal issues.
  • Sellar reconstruction appears to be a key factor in its pathogenesis.
  • Recognizing this entity improves diagnosis and management, with surgical revision offering effective treatment.