Related Experiment Video

Updated: Apr 28, 2026

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
04:09

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers

Published on: March 3, 2023

4.4K

Bone transport accelerates diabetic foot ulcer healing via TGF-β1-mediated angiogenic and osteo-immune coupling

Yan Chen1,2, Xiajie Huang3,4, Chaoquan Yang5

  • 1Department of Bone and Joint Surgery, the First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China. cy003@connect.hku.hk.

Journal of Molecular Histology
|April 27, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
AngiogenesisBone transportDiabetic foot ulcerImmunomodulationTGF‑β1 signalingWound healing

More Related Videos

Visualizing Angiogenesis by Multiphoton Microscopy In Vivo in Genetically Modified 3D-PLGA/nHAp Scaffold for Calvarial Critical Bone Defect Repair
09:34

Visualizing Angiogenesis by Multiphoton Microscopy In Vivo in Genetically Modified 3D-PLGA/nHAp Scaffold for Calvarial Critical Bone Defect Repair

Published on: September 7, 2017

8.6K
Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
13:16

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts

Published on: December 22, 2015

10.6K

Related Experiment Videos

Last Updated: Apr 28, 2026

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
04:09

Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers

Published on: March 3, 2023

4.4K
Visualizing Angiogenesis by Multiphoton Microscopy In Vivo in Genetically Modified 3D-PLGA/nHAp Scaffold for Calvarial Critical Bone Defect Repair
09:34

Visualizing Angiogenesis by Multiphoton Microscopy In Vivo in Genetically Modified 3D-PLGA/nHAp Scaffold for Calvarial Critical Bone Defect Repair

Published on: September 7, 2017

8.6K
Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
13:16

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts

Published on: December 22, 2015

10.6K

Related Concept Videos

Diabetic Foot Ulcer01:31

Diabetic Foot Ulcer

29
Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory...
29
Regulation of Angiogenesis and Blood Supply01:24

Regulation of Angiogenesis and Blood Supply

2.9K
Rapidly dividing tumors, embryos, and wounded tissues require more oxygen than usual, lowering the oxygen concentration in the blood. At low oxygen or hypoxic conditions, an oxygen-sensitive transcription factor called the hypoxia-inducible factor 1 or HIF1 is activated. HIF1 is a dimeric protein of alpha (ɑ) and beta (β) subunits.  Under optimal oxygen conditions, HIF1β is present in the nucleus while HIF1ɑ remains in the cytosol. HIF1ɑ is hydroxylated by prolyl...
2.9K

Articles linked to this work by shared authors, journal, and citation graph.

Genome assembly and subgenomic interactions in Brassica napus additional lines with an alien B05 chromosome from B. juncea.

Plant physiology·2026

Remote periosteal distraction promotes ischemic diabetic foot wound repair associated with VEGF/VEGFR2-related angiogenic responses.

Journal of molecular histology·2026

Safety and antiviral activity of inhaled siRNA SNS812 for treatment of mild-to-moderate COVID-19: a phase 2 randomized trial.

Journal of biomedical science·2026

The hepatic FGFR-ERK-HRG axis regulates heparin-induced thrombocytopenia with thrombosis.

Blood·2026

Targeting the MNK1-MYH9 axis blocks YAP1 recruitment to prevent thrombosis and platelet activation-induced NETosis.

Molecular therapy : the journal of the American Society of Gene Therapy·2026

Low-molecular-weight fucoidan inhibits HMGB1-induced thromboinflammation by modulating HMGB1-TLR4 axis.

European journal of pharmacology·2026

Propolis ameliorates cisplatin-induced nephrotoxicity via activation of Nrf2/HO-1 signaling pathway in rats.

Journal of molecular histology·2026

Quercetin alleviates statin-induced myopathy in adult male rats: insights into the role of oxidative stress, apoptosis, and autophagy-related gene expression (LC3 and LAMP2).

Journal of molecular histology·2026

Histopathological and immunohistochemical characterization of MPTP-associated pancreatic injury and its attenuation by Hexarelin in mice.

Journal of molecular histology·2026

Subacute thyroid injury and relative parathyroid preservation following ionizing radiation: altered HSP-90 immunoexpression in a rat model.

Journal of molecular histology·2026

SIRT3-mediated DRP1 acetylation changes are associated with the restoration of mitochondrial function and alleviation of anterior cruciate ligament injury-induced osteoarthritis.

Journal of molecular histology·2026

The Expression Pattern of HSF1 and Its Regulating HSP70/TLR2 Expression during MO Infection.

Journal of molecular histology·2026

Versatility of Lateral Intercostal Artery Perforator Flaps in Partial Breast Reconstruction: First National Experience of Peru.

European journal of breast health·2026

Orchestrating diabetic wound healing via MoS2 and Zn2+ integrated poly(vinyl alcohol)/dextran hydrogels: decoupling the efficacy-biosafety paradox in mild photothermal therapy.

Journal of materials chemistry. B·2026

Establishment of a cell line-based 3D co-culture model of the endometrium for studying endometrial receptivity.

American journal of physiology. Cell physiology·2026

Thyroid hormone sensitivity indices and hs-CRP as biochemical predictors of arteriovenous fistula maturation in diabetic nephropathy.

Journal of medical biochemistry·2026

Enhancing Regenerative Outcomes: Histopathological Comparison of Calcium Hydroxylapatite Alone and Combined With Platelet-rich Fibrin: A 6-week Study.

Plastic and reconstructive surgery. Global open·2026

Injectable extracellular matrix microparticles for regenerative and biocompatible soft tissue augmentation.

EXCLI journal·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies
Jove
Visualize
Contact Us