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Biomedical CoCrMo/HA Composite Prepared by 3D Printing
Hao Wang1,2, Shaohua Wang3, Jinzhi Ren3
1Co-Creation Institute for Advanced Materials, Shimane University, Matsue 6908504, Shimane, Japan.
ACS Biomaterials Science & Engineering
|April 27, 2026
Summary
A novel cobalt-chromium-molybdenum (CoCrMo)/hydroxyapatite (HA) composite, created using 3D printing, shows superior biocompatibility and mechanical strength for bone repair applications.
Area of Science:
- Biomaterials Engineering
- Materials Science
- Orthopedic Research
Background:
- Traditional metallic implants (e.g., Ti, CoCrMo) have limitations in biocompatibility and density, hindering bone repair.
- Developing advanced biomaterials is crucial for improving orthopedic treatments and patient outcomes.
Purpose of the Study:
- To synthesize and evaluate a novel CoCrMo/hydroxyapatite (HA) composite for biomedical applications.
- To assess the biocompatibility, hemocompatibility, and mechanical properties of the CoCrMo/HA composite.
- To determine the suitability of this composite for human bone repair.
Main Methods:
- Three-dimensional (3D) printing technology was employed for composite synthesis.
- Biocompatibility and blood compatibility were systematically investigated.
- Compressive strength testing was performed to evaluate mechanical properties.
Main Results:
- The CoCrMo/HA composite demonstrated good biocompatibility and blood compatibility, outperforming existing medical materials.
- Enhanced biocompatibility and hemocompatibility were observed over extended durations.
- The composite achieved a compressive strength of 724.4 MPa, meeting requirements for bone repair.
Conclusions:
- The 3D-printed CoCrMo/HA composite offers a promising alternative for bone defect treatment.
- This material exhibits excellent biocompatibility and mechanical integrity for orthopedic applications.
- The study provides a valuable reference for developing next-generation biomedical composites.

