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Drugs for Treatment of Constipation-Predominant IBS01:21

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Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
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Updated: Apr 29, 2026

Acupoint Application Combined with Acupoint Massage for Treating Constipation in a Patient with Chronic Obstructive Pulmonary Disease
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Acupoint Application for Constipation in Thoracolumbar Compression Fracture.

Heng Qiu1, Yong Huang1, Danni Luo2

  • 1Hospital of Chengdu University of Traditional Chinese Medicine.

Journal of Visualized Experiments : Jove
|April 27, 2026
PubMed
Summary
This summary is machine-generated.

Acupoint application effectively treats constipation in patients with thoracolumbar compression fractures (TLFs). This non-invasive method, using specific acupoints and herbs, showed superior results compared to the control group with no severe adverse effects.

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Area of Science:

  • Integrative Medicine
  • Gastroenterology
  • Spinal Cord Injury Management

Background:

  • Thoracolumbar compression fractures (TLFs) frequently lead to constipation, affecting over 70% of patients.
  • Constipation significantly impedes rehabilitation progress in TLF patients.
  • Current treatments may have limitations, necessitating alternative approaches.

Purpose of the Study:

  • To describe and evaluate the efficacy of acupoint application for treating constipation in patients with TLFs.
  • To assess the safety and effectiveness of a specific herbal paste applied to selected acupoints.

Main Methods:

  • A randomized controlled study involving 42 patients with TLFs and constipation.
  • Selected acupoints included Tianshu (ST25), Daheng (SP15), Zusanli (ST36), Shangjuxu (ST37), and Zhigou (TE6).
  • An herbal paste (Rheum officinale) was applied daily for 6 hours over 2 weeks, with efficacy measured by defecation time, symptom scores, quality of life, and pain scales.

Main Results:

  • Constipation improved in both the experimental and control groups after 2 weeks.
  • The experimental group demonstrated statistically significant superiority in all efficacy indicators (p < 0.05).
  • No severe adverse reactions were reported in either group, indicating a favorable safety profile.

Conclusions:

  • Acupoint application offers an effective and safe non-invasive treatment for constipation in TLF patients.
  • This therapeutic approach shows promise for improving patient rehabilitation and quality of life.
  • Future research should focus on larger multi-center studies and optimizing treatment protocols.