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Pediatric Quality of Life Inventory™ Eosinophilic Esophagitis Module: Evaluating Validity and Reliability in Turkish
Hacer Ilbilge Ertoy Karagol1,2, Dilek Yapar2,3,4, Sinem Polat Terece1,2
1Department of Pediatric Allergy, Gazi University School of Medicine, Ankara, Türkiye.
Objective:
The Pediatric Quality of Life Inventory™ (PedsQL™) Eosinophilic Esophagitis (EoE) Module is a specialized instrument designed to assess how EoE affects the quality of life in pediatric patients. This study assesses the Turkish cross-cultural adaptation of the 8-12-year-old version.
Materials And Methods:
As part of the cross-cultural adaptation of the Turkish PedsQL™ EoE Module for children aged 8-12 (Tr-PedsQL™ EoE), linguistic validation, content validity (CnV), construct validity (CsV), and reliability testing were conducted. The CsV was evaluated by correlating Tr-PEESS v2.0 Frequency and Total scores with the Tr-PedsQL™ EoE Symptoms Total, Symptoms I, and Symptoms II scores. Reliability was assessed using Cronbach's alpha for internal consistency and intraclass correlation coefficients (ICC) for test-retest stability.
Results:
The study included 25 children diagnosed with EoE and their parents (n=25). All items showed CnV indexes above 0.8. Good to excellent correlations (r=-0.459 to -0.948) between Tr-PEESS v2.0 (Frequency, Total) and Tr-PedsQL™ EoE Module (Total, Symptoms Total, Symptoms I-II) scores indicate CV. The 8-12-year-old version showed good to excellent internal consistency, with Cronbach's α values of 0.712-0.918 for children and 0.703-0.901 for parents. All ICCs indicated good to excellent test-retest reliability (0.777-0.905 for children, 0.801-0.941 for parents).
Conclusion:
Validity and reliability analyses confirmed that the Tr-PedsQL™ EoE Module is a psychometrically sound instrument for use in both children and their parents. It completed the cross-cultural adaptation process and is appropriate for implementation in both clinical practice and research contexts in Türkiye.
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