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Randomized Clinical Trial of Imagery Stabilization and Rescripting Therapy for Psychiatric Outpatients with
Daeho Kim1, Soorack Ryu2, Ji Young Min3
1Department of Psychiatry, Medical College, Hanyang University, Seoul, Korea. dkim9289@hanyang.ac.kr.
Yonsei Medical Journal
|April 27, 2026
Summary
Imagery Stabilization and Rescripting Therapy (ISRT) shows promise as a safe and effective treatment for posttraumatic stress disorder (PTSD), improving symptoms and quality of life compared to cognitive behavioral therapy (CBT).
Area of Science:
- Psychiatry and Mental Health
- Clinical Psychology
- Trauma Studies
Background:
- Posttraumatic stress disorder (PTSD) significantly impacts adult mental health.
- Novel psychotherapeutic interventions are needed to address PTSD effectively.
- Imagery-based therapies offer a potential alternative for PTSD treatment.
Purpose of the Study:
- To evaluate the safety and efficacy of Imagery Stabilization and Rescripting Therapy (ISRT) for adults with PTSD.
- To compare ISRT with non-trauma-focused cognitive behavioral therapy (CBT) in a randomized clinical trial.
- To assess treatment outcomes at posttreatment and 6-month follow-up.
Main Methods:
- A randomized clinical trial involving 86 adults diagnosed with PTSD.
- Intervention group received 8 sessions of ISRT (n=59).
- Control group received 8 sessions of CBT (n=27).
- Standardized clinical assessments (CAPS-5, HDRS, HARS) and self-report questionnaires were used.
- Data collected at pretreatment, posttreatment, and 6-month follow-up.
Main Results:
- Dropout rates were comparable between ISRT (28.8%) and CBT (25.9%) groups.
- Both completer and intention-to-treat analyses indicated that ISRT favored improvements in clinical status, PTSD symptoms, and quality of life.
- These positive effects were observed posttreatment and at the 6-month follow-up.
Conclusions:
- Imagery Stabilization and Rescripting Therapy (ISRT) demonstrates safety and effectiveness in treating PTSD.
- ISRT presents a viable therapeutic option for individuals suffering from posttraumatic stress disorder.
- Further research may explore ISRT's long-term impact and applicability across diverse PTSD populations.
Keywords:
Posttraumatic stress disorderimagery psychotherapypsychotherapyrandomized clinical trialtreatmentMore Related Videos
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