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[Patient and family predictors of group intervention outcomes in children with attention-deficit/hyperactivity
Xinmei Yang1, Yongqi Wang2, Xiaohua Mo1
1Department of Child and Adolescent Psychiatry, Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Affiliated Brain Hospital of Guangzhou Medical University, Guangzhou 510370, China.
Insights
Children with attention-deficit/hyperactivity disorder (ADHD) who have higher baseline symptoms and hostility traits may show less improvement in group interventions. These factors can help predict treatment outcomes for precision intervention.
Area of Science:
- Child Psychology
- Neurodevelopmental Disorders
- Clinical Intervention Research
Objectives:
To explore individual and family characteristics associated with children's response to group interventions for attention-deficit/hyperactivity disorder (ADHD) based on multidimensional indicators of intervention outcomes.
Methods:
A total of 62 children with ADHD aged 6-9 years participating in an intervention program at the Affiliated Brain Hospital of Guangzhou Medical University from July 2023 to January 2025 were enrolled. All the participants received a standardized group intervention consisting of 8 sessions delivered over 4-6 weeks, focusing on attention training and emotion regulation training. Pre- and post-intervention data were collected using the General Information Questionnaire, the Difficulties in Emotion Regulation Scale (DERS), the Affective Reactivity Index (ARI), the Matson Evaluation of Social Skills with Youngsters (MESSY), and the parent-rated Swanson, Nolan, and Pelham Rating Scale-IV (SNAP-IV). Given the consistency in intervention format and structure between the two groups, data were pooled for modeling analyses. Changes in emotion regulation, inattention, and social skills were used as the outcome indicators. LASSO regression was used to screen 18 baseline variables (8 psychosocial characteristics and 10 demographic and family-background variables), followed by multiple linear regression to identify stable predictors.
Results:
Across the models predicting changes in inattention, irritability, emotion-regulation difficulties, and inappropriately assertive/overconfident, the baseline score of each outcome was a significant positive predictor (β=0.462-0.669, P_BH<0.05). Higher baseline hostile scores predicted less improvement in emotion-regulation difficulties (β=-0.326, P_BH<0.01) and inappropriate assertiveness/overconfidence (β=-0.543, P_BH<0.05).
Conclusions:
This study provides preliminary evidence that baseline symptoms and hostility traits may predict response to group interventions for ADHD, which may help to estimate treatment outcomes before intervention and provide support to precision intervention for children with ADHD.
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