Rethinking the Kinetics of Extended WBC Differential Count and Inflammatory Index Marker in Secondary Dengue...

Dengue infection is an emerging disease that continues to present a serious global public health challenge, contributing substantially to morbidity and mortality. Clinical and diagnostic management remain challenging due to the rapid progression of dengue among patients. This case report presents a comprehensive approach integrating clinical assessment with laboratory findings for the evaluation and management of secondary dengue infection. Key points highlighted include: (1) the negative kinetics of dengue antigen and antibody detection; and (2) the dynamic changes observed in extended white blood cell differential counts and inflammatory marker functions in relation to clinical outcomes. In summary, monitoring the extended white blood cell differential count and inflammatory index markers offers substantial value in detecting rapid escalation of disease severity. Furthermore, these parameters are notable for their repeatability, feasibility, and cost-effectiveness, thereby enhancing patient management efficiency.