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Comparative Study between Conventional Laparoscopic Nissen Fundoplication and Modified Nissen Fundoplication: A
Khaled Mohamed Albeialy1, Mohamed Mahfouz Mohamed1, Mohamed Ibrahim Hassan1
1Department of General Surgery, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
La Clinica Terapeutica
|April 28, 2026
Summary
Modified Nissen fundoplication (MNF) shows comparable safety to conventional Laparoscopic Nissen fundoplication (NF) for GERD. MNF may reduce certain postoperative complications, but larger studies are needed to confirm long-term efficacy.
Area of Science:
- Gastroenterology
- Surgical Innovation
- Reflux Management
Background:
- Laparoscopic Nissen fundoplication (NF) is the established anti-reflux procedure.
- Modified Nissen fundoplication (MNF) aims to improve hiatal stabilization and reduce GERD recurrence.
- MNF incorporates additional sutures to fixate the esophagus to the right and left crus.
Purpose of the Study:
- To compare conventional Laparoscopic Nissen Fundoplication (NF) and Modified Nissen Fundoplication (MNF).
- To evaluate postoperative complications, specifically dysphagia and GERD symptom recurrence.
- To assess the safety and efficacy of MNF versus NF.
Main Methods:
- Prospective randomized controlled trial.
- Conducted at Ain Shams University Hospitals from January 2023 to January 2025.
- Included patient recruitment and one year of follow-up.
Main Results:
- A statistically significant difference was observed in postoperative hiccups and left shoulder pain between NF and MNF.
- MNF was found to be safely performable by experienced surgeons.
- No increased morbidity or complication rates were associated with MNF compared to NF in this study.
Conclusions:
- The study suggests MNF can be performed safely without increased complications.
- Limited sample size and follow-up duration may affect generalizability.
- Further research with larger cohorts and longer follow-up is recommended to validate MNF's long-term outcomes.
