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Related Concept Videos

Facilitated Transport01:19

Facilitated Transport

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The chemical and physical properties of plasma membranes cause them to be selectively permeable. Since plasma membranes have both hydrophobic and hydrophilic regions, substances need to be able to transverse both regions. The hydrophobic area of membranes repels substances such as charged ions. Therefore, such substances need special membrane proteins to cross a membrane successfully. In  facilitated transport, also known as facilitated diffusion, molecules and ions travel across a...
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Short-distance Transport of Resources02:12

Short-distance Transport of Resources

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Short-distance transport refers to transport that occurs over a distance of just 2-3 cells, crossing the plasma membrane in the process. Small uncharged molecules, such as oxygen, carbon dioxide, and water, can diffuse across the plasma membrane on their own. In contrast, ions and larger molecules require the assistance of transport proteins due to their charge or size. Transport across membranes also occurs within individual cells, playing a variety of essential roles for the plant as a whole.
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The Significance of Membrane Transport01:44

The Significance of Membrane Transport

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The transport of solutes across the cell membrane is essential for metabolic processes, like maintaining cell size and volume, generating the action potential, exchanging nutrients and gases, etc. Membrane transport can be either passive or active. It can be simple diffusion, facilitated, or mediated transport aided by transport proteins such as transporters and channels.
Transporters facilitate either an active or passive movement of solutes. They can allow a single-molecule transport down its...
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Facilitated Transport01:19

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The chemical and physical properties of plasma membranes cause them to be selectively permeable. Since plasma membranes have both hydrophobic and hydrophilic regions, substances need to be able to transverse both regions. The hydrophobic area of membranes repels substances such as charged ions. Therefore, such substances need special membrane proteins to cross a membrane successfully. In  facilitated transport, also known as facilitated diffusion, molecules and ions travel across a...
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Transport Across the Golgi01:26

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While it is unclear how molecules move between adjacent Golgi cisternae, it is apparent that the molecules move from cis- cisterna, the entry face, to the trans- cisterna, the exit face. Experiments initially suggested vesicles that bud from one cisterna and fuse with the next cisterna to transport proteins between the cisternae. This vesicular transport model describes the Golgi apparatus as a relatively static structure with a unique enzyme composition in each cisterna. Molecules are...
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Carrier-mediated transport is a pivotal process in drug absorption, particularly for lipid-insoluble drugs, and encompasses facilitated diffusion and active transport. Facilitated diffusion allows drugs to move along their concentration gradient without energy expenditure, while active transport utilizes ATP to drive drug movement against this gradient.
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Related Experiment Video

Updated: Jul 2, 2026

In Vivo Application of TurboID-based Proximity Labeling in Drosophila melanogaster
09:59

In Vivo Application of TurboID-based Proximity Labeling in Drosophila melanogaster

Published on: June 13, 2025

Domain Adaptation With Additional Features via Label-Aware and Graph-Based Fused Gromov-Wasserstein Optimal

Toshimitsu Aritake1, Hideitsu Hino2,3

  • 1Hitotsubashi University, Kunitachi, Tokyo 186-0004, Japan toshimitsu.aritake@r.hit-u.ac.jp.

Neural Computation
|April 28, 2026
PubMed
Summary
This summary is machine-generated.

This study introduces Label-Aware and Graph-Based Fused Gromov-Wasserstein Optimal Transport (LAGB-FGW) for domain adaptation with new target features. LAGB-FGW effectively transfers labels by integrating source information and target structure, outperforming existing methods.

Related Experiment Videos

Last Updated: Jul 2, 2026

In Vivo Application of TurboID-based Proximity Labeling in Drosophila melanogaster
09:59

In Vivo Application of TurboID-based Proximity Labeling in Drosophila melanogaster

Published on: June 13, 2025

Area of Science:

  • Machine Learning
  • Computer Vision
  • Data Science

Background:

  • Domain adaptation typically assumes shared feature spaces, challenged by new target-only features at test time.
  • Existing methods often fail when target-specific features emerge post-training, violating core assumptions.
  • Transductive domain adaptation requires joint inference for unlabeled target data available during training.

Purpose of the Study:

  • To develop a novel domain adaptation method, LAGB-FGW, capable of handling new target-only features.
  • To address the challenge of distributional shift and feature space discrepancies in domain adaptation.
  • To improve label transfer accuracy in scenarios with evolving target data characteristics.

Main Methods:

  • Label-Aware and Graph-Based Fused Gromov-Wasserstein Optimal Transport (LAGB-FGW) is proposed.
  • The method embeds label discrepancy into the source metric and uses a K-NN graph on target features.
  • It jointly solves standard Optimal Transport (OT) and Gromov-Wasserstein OT for label transfer.

Main Results:

  • LAGB-FGW demonstrated consistent superior performance across four synthetic benchmarks.
  • The method achieved state-of-the-art results on the HAR70+ human-activity dataset.
  • Outperformance highlights the benefit of combining source label information with graph-based structural cues.

Conclusions:

  • LAGB-FGW effectively adapts models when new target features are available only at test time.
  • The approach successfully leverages both common and additional features for robust label transfer.
  • This method offers a significant advancement for domain adaptation in dynamic environments.