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MRI Diagnosis of Meniscus Tears in the Knee: An Updated Systematic Review and Meta-analysis
Jie C Nguyen1,2, Carlos Yaya-Quezada1, Wondwossen T Lerebo1
1Section of Musculoskeletal Imaging, Department of Radiology, Children's Hospital of Philadelphia, 3401 Civic Center Blvd, Philadelphia, PA 19104.
Abstract:
Background Updated benchmarks are needed on the diagnostic performance of MRI for detecting meniscus tears compared with arthroscopy. Purpose To conduct an updated systematic review and meta-analysis on the diagnostic performance of MRI in the detection of tears of the native menisci compared with arthroscopy and with subgroup analyses to identify factors that impact accuracy. Materials and Methods A literature search was conducted using PubMed, Scopus, and Embase databases to identify peer-reviewed publications on MRI diagnosis of meniscus tears using knee arthroscopy as the reference standard. Random-effects models, pooled weighted sensitivity and specificity, and summary receiver operating characteristic curve analyses were used to determine diagnostic performance, changes according to publication year, and differences based on study design, patient characteristics, imaging parameters, and diagnostic criteria for tears. A meta-regression model was also used. Results Seventy-five studies (published 1986-2023) from 28 countries included 8507 patients (8517 knees). Pooled weighted sensitivity was higher for medial tears (91.0% [95% CI: 89.3, 92.4]) than for lateral tears (78.5% [95% CI: 74.5, 82.0]). In contrast, specificity was higher for lateral tears (94.0% [95% CI: 92.5, 95.3]) than for medial tears (87.7% [95% CI: 85.2, 89.8]). Specificity for diagnosing lateral tears decreased over the years (P = .01). The highest pooled sensitivity for lateral tears was found in studies using both surfacing linear signal intensity and meniscus distortion for diagnosis (81.1%) compared with studies using only signal intensity (79.2%) or not reporting criteria (60.8%) (P = .02); likewise in meta-regression, using both surfacing signal intensity and meniscus distortion was a predictor of higher performance compared with not reporting criteria (adjusted odds ratio, 3.74 [95% CI: 1.37, 10.18]; P = .01). No differences in sensitivity or specificity (P value range, .29-.59) were found between studies using one or more versus two or more images for diagnosing tears in either meniscus. Conclusion The reported accuracy of knee MRI for meniscus tears was consistently high, regardless of individual study designs, with sensitivity higher for the medial meniscus and specificity higher for the lateral meniscus. © RSNA, 2026 Supplemental material is available for this article.
Insights
Updated benchmarks show magnetic resonance imaging (MRI) has high accuracy for detecting meniscus tears, with better sensitivity for medial tears and higher specificity for lateral tears. Diagnostic performance remains consistently high across various study designs.
Area of Science:
- Orthopedics
- Radiology
- Medical Imaging
Background:
- Establishing updated diagnostic performance benchmarks for MRI in detecting meniscus tears is crucial.
- Arthroscopy serves as the gold standard reference for evaluating MRI accuracy.
Purpose of the Study:
- To perform an updated systematic review and meta-analysis on the diagnostic performance of MRI for native meniscus tears.
- To identify factors influencing MRI accuracy through subgroup analyses.
Main Methods:
- A comprehensive literature search was conducted across PubMed, Scopus, and Embase.
- Random-effects models, pooled sensitivity/specificity, and ROC curve analyses were employed.
- Meta-regression was used to explore factors impacting diagnostic performance.
Main Results:
- Seventy-five studies including 8507 patients were analyzed.
- Pooled sensitivity was higher for medial tears (91.0%) than lateral tears (78.5%).
- Pooled specificity was higher for lateral tears (94.0%) than medial tears (87.7%). Specificity for lateral tears declined over time.
- Using both signal intensity and meniscus distortion criteria improved lateral tear detection sensitivity.
Conclusions:
- Knee MRI demonstrates consistently high accuracy for meniscus tear detection.
- Sensitivity is generally higher for medial meniscus tears, while specificity is higher for lateral meniscus tears.
- Diagnostic accuracy is robust across different study designs and patient characteristics.
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