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Capsular contraction around silicone mammary prostheses.

R Gayou, R Rudolph

Annals of Plastic Surgery

|January 1, 1979

Summary

Capsular contracture, a common complication of silicone breast implants, remains unpredictable despite surgical techniques. Research reviews wound healing, fibroblast activity, and potential treatments like steroids to prevent this scar tissue formation.

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Area of Science:

Plastic Surgery
Biomaterials Science
Wound Healing Research

Background:

Capsular contracture is the most frequent complication following augmentation mammaplasty with silicone implants.
This unpredictable complication occurs with all implant types, irrespective of preventive surgical methods.
Understanding the biological response to implants is crucial for mitigating adverse outcomes.

Purpose of the Study:

To review current clinical practices for managing and preventing capsular contracture after silicone implant augmentation.
To explore the biological processes involved in wound healing and scar formation around breast implants.
To discuss the potential role of implant characteristics and pharmacological interventions in capsular contraction.

Main Methods:

Review of existing clinical practices and surgical techniques.
Analysis of the biological processes of wound healing and fibroblast activity around silicone implants.
Discussion of the physical and chemical properties of silicone implants and their potential impact.
Evaluation of the efficacy of steroid use and other drug treatments.

Main Results:

Wound healing around silicone implants follows a typical inflammatory and collagen synthesis pattern.
Breast capsules exhibit contractile fibroblasts, similar to other scar tissues.
Changes in silicone implants within tissues are detectable but not currently linked to capsular contraction.
The effectiveness of steroid use for preventing contraction is debated, with other drug treatments under investigation.

Conclusions:

Capsular contracture is a complex complication influenced by biological responses to silicone implants.
Further research is needed to elucidate the precise mechanisms and develop effective preventive strategies.
Investigating implant material properties and exploring novel pharmacological agents are key areas for future development.

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